AMACR anticorps

N° du produit ABIN115447

Cet anticorps Lapin Polyclonal détecte spécifiquement AMACR dans IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour AMACR anticorps (ABIN115447)

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMACR est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-AMACR anticorps

Specificité: Reacts to P504S Alpha-Methylacyl-CoA Racemace.
Cellular Localization: Cytoplasmic.

Purification: Purified

Immunogène: A synthetic human AMACR peptide.

Information d'application

Indications d'application: Immunohistochemistry on Formalin-Fixed Paraffin Embedded Sections: 1/25-1/50 in anABC method (30 minutes at room temperature). Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining. Recommended Positive Control: Prostate carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur AMACR

Antigène: AMACR (alpha-Methylacyl-CoA Racemase (AMACR))

Autre désignation: AMACR / RACE

Sujet: P504S (AMARC) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of P504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.Synonyms: 2-methylacyl-CoA racemase, Alpha-methylacyl-CoA racemase, P504S

ID gène: 23600

NCBI Accession: NP_055139

UniProt: Q9UHK6

Pathways: Monocarboxylic Acid Catabolic Process